Here are the top seven U.S. healthcare leaders on the list, ranked on descending net worth.
1. Thomas Frist Jr., MD, ($21.6 billion) is a founder and major shareholder of Nashville, Tenn.-based HCA Healthcare.
2. Carl Cook ($10.4 billion) is owner and CEO of Cook Group, a medical device manufacturer based in Bloomington, Ind.
3. Patrick Soon-Shiong, MD, ($8.4 billion) invented the cancer drug Abraxane.
4. Ronda Stryker ($7.8 billion) is director of and the largest individual shareholder in Stryker Corp., a medical equipment company.
5. Li Ge, PhD, ($6.1 billion) is chairman and CEO of WuXi AppTec, a global research and development and manufacturing services company.
6. Pat Stryker ($6 billion) is a shareholder of Stryker Corp., a medical equipment company founded by her grandfather.
7. Reinhold Schmieding ($6 billion) is the founder and president of Arthrex, a surgical device maker.